of course.
you can read about it in the pgfmanual in chapter 39.7:
\usepackage[tikz]
\usetikzlibrary[shapes.callout]
\starttext
\starttikzpicture
\node[ellips callout, draw] {Hallo!};
\stoptikzpicture
\stoptext
using the options
callout relative pointer=(coordinate)
and
callout absolute pointer=(coordinate)
, you can modify where it points to, using standard node options you can modify other aspects (positioning, padding, width, height, color, line thickness, …)
beware: i have not tested above code, but it should be obvious.
Philipp